2-氨基-4-氯苯甲酸Product Identification
【Product Name】
4-Chloroanthranilic acid
【Synonyms】
2-Amino-4-chlorobenzoic acid
4-Chloro-2-aminobenzoic acid
【CAS】89-77-0
【Formula】C7H6ClNO2
【Molecular Weight】171.58
【EINECS】201-938-5
【RTECS】DG1570000
【RTECS Class】Drug
【Beilstein/Gmelin】743349
【Beilstein Reference】4-14-00-01072
Physical and Chemical Properties
【Appearance】Beige brown solid.
【Solubility in water】Soluble
【Melting Point】240
【Boiling Point】330
【pKa/pKb】4.71 (pKa)
【Partition Coefficient】1.35
First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
【Storage】Store in a cool, dry place. Store in a tightly closed container.
【Handling】Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Hazards Identification
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
【Inhalation】May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema.
【Skin】Causes skin irritation.
【Eyes】Causes eye irritation.
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Fire Fighting Measures
【Flash Point】> 100
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use foam, dry chemical, or carbon dioxide.
Accidental Release Measures
【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container. Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability and Reactivity
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Carbon monoxide, oxides of nitrogen, carbon dioxide.