Product Identification
【Product Name】Methyl 4-hydroxy-3-methoxybenzoate
【Synonyms】Vanillic acid, methyl este 　香草酸甲酯
【CAS】3943-74-6
【Formula】C9H10O4
【Molecular Weight】182.17
【EINECS】223-525-9
【RTECS】DH2430000
【RTECS Class】Other
【Beilstein/Gmelin】1369113
【Beilstein Reference】3-10-00-01410

Physical and Chemical Properties
【Appearance】Slightly yellow.
【Solubility in water】Insoluble
【Boiling Point】285℃
【Vapor Pressure】0.002 (25℃)
【pKa/pKb】8.36 (pKa)
【Partition Coefficient】1.82
【Heat Of Vaporization】43.6 kJ/mol

First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
【Inhalation】Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage
【Storage】Store in a cool, dry place. Keep container closed when not in use.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear chemical ggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】The toxicological properties of this material have not been investigated.
【Poison Class】5

Fire Fighting Measures
【Flash Point】120℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.

Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment.

Stability and Reactivity
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Irritating and toxic fumes and gases.

Hazards Identification
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36