Product Identification
【Product Name】Carbonothioic dihydrazide
【Synonyms】1,3-Diamino-2-thiourea；硫代卡巴肼
【CAS】2231-57-4
【Formula】CH6N4S
【Molecular Weight】106.17
【EINECS】218-769-8
【RTECS】FF2975000
【RTECS Class】Agricultural Chemical and Pesticide; Primary Irritant
【Beilstein/Gmelin】506657
【Beilstein Reference】4-03-00-00388

Physical and Chemical Properties
【Appearance】Crystalline needles and plates.
【Solubility in water】Very soluble
【Boiling Point】230℃
【Vapor Pressure】0.07 (25℃)
【pKa/pKb】11.99 (pKb)
【Partition Coefficient】-1.33
【Heat Of Vaporization】46.7 kJ/mol
【Usage】Thiocarbohydrazide is used in electron microscopy to produce electron-opaque deposits for ultrastructural analysis.

First Aid Measures
【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage
【Storage】Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. May form flammable dust-air mixtures. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Avoid mechanical shock and friction. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or flames.

Hazards Identification
【Ingestion】May be fatal if swallowed. The toxicological properties of this substance have not been fully investigated. May cause central nervous system effects.
【Inhalation】Inhalation of dust may cause respiratory tract irritation.
【Skin】May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
【Eyes】Dust may cause mechanical irritation.
【Hazards】When heated to decomposition it emits very toxic fumes of nitrogen oxides and sulfur oxides.
【EC Risk Phrase】R 5 26/28 21
【EC Safety Phrase】S 15 28 36/37/39 45
【UN (DOT)】2811

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures
【Flash Point】93℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Flammable solid. Material is shock sensitive and potentially explosive. Greatly increases the burning rate of combustible materials. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.
【Fire Potential】Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity
【Incompatibilities】Strong oxidizing agents, strong acids.
【Stability】Substance is shock sensitive and thermally unstable.
【Decomposition】Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】2811
【Hazard Class】6.1
【Packing Group】I; II; III