Product Identification
【Product Name】3-Hydroxy-2-picoline
【Synonyms】3-羟基-2-甲基吡啶
【CAS】1121-25-1
【Formula】C6H7NO
【Molecular Weight】109.12
【EINECS】214-327-3
【Beilstein/Gmelin】107937
【Beilstein Reference】5-21-02-00135

Physical and Chemical Properties
【Appearance】Off-white to tan powder.
【Solubility in water】Very soluble
【Melting Point】128 - 130℃
【Boiling Point】287℃
【Vapor Pressure】0.0015 (25℃)
【pKa/pKb】4.95 (pKb)
【Partition Coefficient】.3
【Heat Of Vaporization】547. kJ/mol
【Heat Of Combustion】-3188 kJ/mol

First Aid Measures
【Ingestion】Get medical aid. Wash mouth out with water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Store in a cool, dry place. Store in a tightly closed container.
【Handling】Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification
【Ingestion】May cause irritation of the digestive tract. May be harmful if swallowed. Ingestion of large amounts may cause nausea and vomiting, rigidity or convulsions. Continued exposure can produce coma, dehydration, and internal organ
【Inhalation】Causes respiratory tract irritation. May be harmful if inhaled.
【Skin】Causes skin irritation. May be harmful if absorbed through the skin.
【Eyes】Causes eye irritation.
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36

Exposure Controls/Personal Protection
【Personal Protection】Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures
【Flash Point】127℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures
【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity
【Stability】No data.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Nitrogen oxides, carbon monoxide, carbon dioxide.